Nicholas Simon received his PhD in psychology in 2010 from Texas A&M University, where he studied the neural and pharmacological substrates of cost-benefit decision-making behavior under Barry Setlow.
He joined the Moghaddam Lab as a postdoctorate researcher in 2010. Nick's current research projects involve the use of electrophysiological recording techniques to analyze the functional interaction between prefrontal cortical structures during learning and behavior.
Publications
Simon, N.W., Setlow, B. (2006) Post-training amphetamine enhances memory consolidation in appetitive Pavlovian conditioning: Implications for drug addiction. Neurobiology of Learning and Memory, 86:305-310.
Simon, N.W., Mendez, I.A., Setlow, B. (2007) Cocaine exposure causes long-term increases in impulsive choice behavior. Behavioral Neuroscience, 121:543-549.
Mendez, I.A., Montgomery, K.S., LaSarge, C.L., Simon, N.W., Bizon, J.L., Setlow, B. (2008) Long-term deficits in spatial learning produced by cocaine exposure. Neurobiology of Learning and Memory, 89:185-191.
Simon, N.W., Mendez, I.A., Setlow, B. (2009) Prior amphetamine exposure alters approach strategy during Pavlovian conditioning. Psychopharmacology, 202:699-709.
Simon, N.W., Gilbert, R.J., Mayse JD, Setlow, B. (2009) Balancing risk and reward: A rat model of risky decision-making. Neuropsychopharmacology, 34:2208-2217.
Setlow, B., Mendez, I.A., Mitchell, M.R., Simon, N.W. (2009) The effects of chronic administration of drugs of abuse on discounting of delayed rewards (impulsive choice) in animal models. Behavioural Pharmacology, 20:380-389.
Simon, N.W., LaSarge, C.L., Williams, M.T., Montgomery, K.S., Mendez, I.A., Setlow, B., Bizon, J.L. (2010) Good things come to those who wait: Impulsive choice is attenuated in aged Fischer 344 rats. Neurobiology of Aging, 31(5):853-62.
Mendez, I.A., Simon, N.W., Hart, N., Mitchell, M.R., Nation, J.R., Wellman, P.J., Setlow, B. (2010) Self-administered cocaine causes lasting increases in impulsive choice in a delay-discounting task. Behavioral Neuroscience, 124:470-7.
Mitchell, M.R., Vokes, C.M., Blankenship, A.L., Simon, N.W., Setlow, B. (2011) Effects of acute administration of nicotine, amphetamine, diazepam, morphine, and ethanol on risky decision-making rats. Psychopharmocology, 218:703-12.
Simon, N.W., Montgomery, K.S., Beas, B.S., Lasarge, C.L., Mendez, I.A., Mitchell, M.R., Baneulos, C., Vokes, C.M., Woller, S., Taylor, A., Bizon, J.L., Setlow, B. (2011) Dopaminergic modulation of risky decision-making. The Journal of Neuroscience, 31: 17460-70.
Simon, N.W. and Setlow, B. (2012) Modeling risky decision-making in rodents. Methods of Molecular Biology, 829: 165-75.
Gilbert, R.J., Mitchell, M.R., Simon, N.W., Banuelos, C., Setlow, B., and Bizon, J.L. (2012) Risk, reward, and decision-making in rodent model of cognitive aging. Frontiers in Decision Neuroscience, 5: 144.